Download Berne & Levy Physiology (8th Ed) by Koeppen & Stanton

Download Berne & Levy Physiology (8th edition) by Bruce M. Koeppen and Bruce A. Stanton.

Berne & Levy Physiology (8th Ed.) by Bruce M. Koeppen and Bruce A. Stanton is a definitive resource that seamlessly integrates fundamental concepts of physiology with clinical relevance. This edition maintains the textbook’s renowned clarity and comprehensive coverage while incorporating the latest advancements in the field.

Enhanced with vivid illustrations and real-world applications, it fosters a deeper understanding of physiological processes and their implications for health and disease. Designed for medical students, educators, and healthcare professionals, this text not only serves as a foundational guide but also as a catalyst for critical thinking and lifelong learning in physiology.

According to the authors, “In keeping with previous editions of this textbook, we have focused on highlighting broad concepts while minimizing the collection of isolated facts. Each chapter has been crafted to ensure the text is clear, accurate, and up to date. We have incorporated both clinical and molecular insights within each section, as feedback has shown that this integration provides essential clinical context and fresh perspectives on physiological phenomena at the cellular and molecular levels.

The human body is composed of billions of cells organized into various tissues (such as muscle, epithelium, and nervous tissue) and organ systems (including the nervous, cardiovascular, respiratory, renal, gastrointestinal, endocrine, and reproductive systems). For these tissues and organ systems to function optimally, certain fundamental conditions must be met. Primarily, the survival of cells is essential.

This survival hinges on sufficient cellular energy, the maintenance of a suitable intracellular environment, and protection against a hostile external world. Once cell survival is assured, cells can perform their specialized functions—such as contraction in skeletal muscle cells. Ultimately, the coordination and regulation of the functions of cells, tissues, and organs are paramount. These functions form the essence of physiology and are explored throughout this book, beginning with an introduction to these fundamental concepts.

Humans inhabit diverse environments and frequently transition between them, necessitating the body’s ability to swiftly adapt to challenges posed by variations in temperature and the availability of food and water. Such adaptability requires the coordinated function and regulation of cells across different tissues and organs.

The nervous and endocrine systems play crucial roles in this coordination, regulating functions that can occur rapidly (within seconds to minutes), such as the modulation of cellular fuel levels in the blood, or over longer periods (days to weeks), as seen in acclimatization when transitioning from cool to hot environments or shifting from a high-salt to a low-salt diet.

The functions of the human body involve complex processes at multiple levels, which this book aims to elucidate. While the focus is primarily on the normal functioning of the human body, discussions of diseases and abnormal functions are also included, as they often highlight physiological processes and principles in their extreme forms.”

Section 1: Cellular Physiology

Principles of Cell and Membrane Function
Homeostasis: Volume and Composition of Body Fluid Compartments
Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression

Section 2: Neurophysiology

The Nervous System: Introduction to Cells and Systems
Generation and Conduction of Action Potentials
Synaptic Transmission
The Somatosensory System
The Special Senses
Organization of Motor Function
Integrative Functions of the Nervous System
The Autonomic Nervous System and Its Central Control

Section 3: Muscle Physiology

Skeletal Muscle Physiology
Cardiac Muscle
Smooth Muscle

Section 4: Cardiovascular Physiology

Overview of Circulation
Elements of Cardiac Function
Properties of the Vasculature
Regulation of the Heart and Vasculature
Integrated Control of the Cardiovascular System

Section 5: Respiratory Physiology

Introduction to the Respiratory System
Static Lung and Chest Wall Mechanics
Dynamic Lung and Chest Wall Mechanics
Ventilation, Perfusion, and Ventilation/Perfusion Relationships
Oxygen and Carbon Dioxide Transport
Control of Respiration
Host Defense and Metabolism in the Lung

Section 6: Gastrointestinal Physiology

Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract
The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal
The Gastric Phase of the Integrated Response to a Meal
The Small Intestinal Phase of the Integrated Response to a Meal
The Colonic Phase of the Integrated Response to a Meal
Transport and Metabolic Functions of the Liver

Section 7: Renal Physiology