Free download An Introduction to Genetic Engineering (4th edition) authored by Desmond S. T. Nicholl.
Desmond S. T. Nicholl’s An Introduction to Genetic Engineering is a comprehensive and accessible textbook that serves as an excellent resource for students and educators alike. Now in its fourth edition, the book continues to provide a clear and concise introduction to the complex and rapidly evolving field of genetic engineering.
The textbook is well-structured, beginning with fundamental concepts in molecular biology and gradually progressing to more advanced topics in genetic engineering. Nicholl takes care to build a solid foundation, making sure that readers are well-equipped to understand the intricacies of gene manipulation, recombinant DNA technology, and the various applications of genetic engineering.
One of the book’s strengths is its logical flow. It starts with the basics, such as DNA structure and function, and then delves into more specialized areas like cloning vectors, gene cloning, and the techniques used in genetic engineering. The later chapters address the ethical and social implications of genetic engineering, providing a balanced view that encourages critical thinking.
Nicholl’s writing is both clear and engaging, which is crucial for a subject that can be dense and technical. He explains complex concepts in a way that is easy to understand without oversimplifying the content. The use of diagrams, illustrations, and summary boxes further enhances the learning experience, helping to break down challenging ideas into manageable parts.
The textbook is also peppered with examples and case studies that demonstrate the practical applications of genetic engineering in various fields, such as medicine, agriculture, and biotechnology. These real-world examples help to contextualize the material and show the relevance of genetic engineering in everyday life.
The fourth edition includes updates that reflect the latest advancements in genetic engineering, ensuring that the content is current and relevant. Nicholl has also expanded on certain topics to provide more depth, particularly in areas that have seen significant technological advancements, such as CRISPR-Cas9 and other genome-editing technologies. This edition also addresses recent ethical debates and regulatory considerations, which are increasingly important in the field.
Contents
Part 1: Genetic Engineering in Context
- Introduction
- The Story of DNA
- Brave New World or Genetic Nightmare?
Part 2: The Basis of Genetic Engineering
- Introducing Molecular Biology
- The Tools of the Trade
- Working with Nucleic Acids
Part 3: The Methodology of Gene Manipulation
- Host Cells and Vectors
- Cloning Strategies
- The Polymerase Chain Reaction
- Selection, Screening and Analysis of Recombinants
- Bioinformatics
- Genome Editing
Part 4: Genetic Engineering in Action
- Investigating Genes, Genomes and ‘Otheromes’
- Genetic Engineering and Biotechnology
- Medical and Forensic Applications of Gene Manipulation
- Transgenic Plants and Animals
- The Other Sort of Cloning
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