Explore Casarett & Doull’s Essentials of Toxicology (4th edition) by Curtis D. Klaassen & John B. Watkins.
For over 25 years, Casarett & Doull’s Toxicology: The Basics of Poisons has been a benchmark for comprehensive, academic, and authoritative toxicology resources presented in a clear and engaging manner. Drawing on the key principles and concepts from this renowned text, Casarett & Doull’s Essentials of Toxicology offers an accessible and highly readable introduction to the science and clinical aspects of medical toxicology, featuring insights from over 60 distinguished contributors.
This full-color edition builds on the success of its predecessors, incorporating significant updates to enhance its clinical relevance for students and beginners in toxicology, pharmacology, pharmacy, and environmental sciences. Chapter-ending self-assessment questions and additional learning features make the book a highly effective and efficient educational tool.
The fourth edition of Essentials of Toxicology provides a concise summary of the principles and concepts of toxicology as presented in the ninth edition of Casarett & Doull’s Toxicology: The Basic Science of Poisons. This edition defines the broad field of toxicology in a succinct manner and incorporates essential concepts from anatomy, physiology, and biochemistry to aid in understanding the principles and mechanisms underlying toxicant action.
Building on the foundation established in Casarett & Doull’s Toxicology, this book is structured into seven comprehensive units: (1) General Principles of Toxicology, (2) Disposition of Toxicants, (3) Non-organ-directed Toxicity, (4) Target Organ Toxicity, (5) Toxic Agents, (6) Environmental Toxicology, and (7) Applications of Toxicology. Each chapter includes key points and review questions to enhance learning.
This text is designed to support students in undergraduate and graduate toxicology courses, as well as those from related disciplines, in developing a solid understanding of the subject. Feedback from readers on the previous edition has been invaluable, and suggestions for further improvements are welcomed to refine future editions.
Contents
Unit 1: General Principles of Toxicology
- The Evolving Journey of Toxicology: A Historical Glimpse
- Principles of Toxicology
- Mechanisms of Toxicity
- Risk Assessment
Unit 2: Disposition of Toxicants
- Absorption, Distribution, and Excretion of Toxicants
- Biotransformation of Xenobiotics
- Toxicokinetics
Unit 3: Non-Organ-Directed Toxicity
- Chemical Carcinogenesis
- Genetic Toxicology
- Developmental Toxicology
Unit 4: Target Organ Toxicity
- Toxic Responses of the Blood
- Toxic Responses of the Immune System
- Toxic Responses of the Liver
- Toxic Responses of the Kidney
- Toxic Responses of the Respiratory System
- Toxic Responses of the Nervous System
- Toxic Responses of the Cornea, Retina, and Central Visual System
- Toxic Responses of the Heart and Vascular System
- Toxic Responses of the Skin
- Toxic Responses of the Endocrine System
- Toxic Responses of the Reproductive System
Unit 5: Toxic Agents
- Toxic Effects of Pesticides
- Toxic Effects of Metals
- Toxic Effects of Solvents and Vapors
- Toxic Effects of Radiation and Radioactive Materials
- Toxic Effects of Plants and Animals
- Food Toxicology: Fundamental and Regulatory Aspects
- Toxic Effects of Calories
- Nanoparticle Toxicology
Unit 6: Environmental Toxicology
- Ecotoxicology
- Air Pollution
Unit 7: Applications of Toxicology
- Analytical and Forensic Toxicology
- Clinical Toxicology
- Occupational Toxicology
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